The three pillars for Paraguay’s 2030 development goals: poverty reduction and social development, inclusive economic growth, and economic connectivity with international markets (NDC, 2015) could be affected by impacts of climate changes. The Paraguayan economy and population are highly vulnerable to projected impacts from climate change. Paraguay’s key economic sectors, namely, agricultural production and animal husbandry and hydroelectric energy are sensitive to environmental conditions. The historical connection between flooding events and droughts with food security and public health reflect the exposure of these sectors to climate change impacts. In addition to hydroelectric production, the economy depends on navigable rivers for transportation, which could be impacted by changes in river flows sensitive to climate change. Agricultural production is also vulnerable to rising temperatures and changing precipitation. Paraguay’s priority adaptation sectors identified in their 2015 Nationally Determined Contribution are: water resources, forestry, agricultural and livestock production, land management, energy, infrastructure, health and sanitation, disaster risk management and early warning systems. National adaptation plans take special consideration for a gender perspective to climate adaptation as well as adaptation plans for indigenous communities. The National Environmental Secretary (Secretaría del Ambiente, SEAM) coordinates adaptation action through the National Climate Change office (Oficina Nacional de Cambio Climático, ONCC) that is supported by the National Commission for Climate Change (Comisión Nacional de Cambio Climático, CNCC). Paraguay published a National Plan for Climate Change Adaptation in 2017.